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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK7 All Species: 6.06
Human Site: S623 Identified Species: 10.26
UniProt: Q13164 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13164 NP_002740.2 816 88386 S623 P Q P Q S A G S T S G P V P Q
Chimpanzee Pan troglodytes XP_511332 494 55249 V316 L F P G K N Y V H Q L Q L I M
Rhesus Macaque Macaca mulatta XP_001099721 816 88521 S623 P Q P Q P V G S T S G P V P Q
Dog Lupus familis XP_546651 731 80417 T553 G T S G G P S T D P L A G L V
Cat Felis silvestris
Mouse Mus musculus Q9WVS8 806 87714 G611 G P V S Q S T G P L Q P A G S
Rat Rattus norvegicus P0C865 806 87808 S609 P N G P V S Q S T A P L Q P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518277 258 29416 A79 G M A R G L C A A P A E R Q Y
Chicken Gallus gallus
Frog Xenopus laevis P26696 361 41238 H183 V A D P D H D H T G F L T E Y
Zebra Danio Brachydanio rerio NP_001013469 862 94944 R622 K R K K R Q E R A M E R K R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780133 1079 118303 D787 K K K K N R H D K E E K K Q P
Poplar Tree Populus trichocarpa XP_002302599 372 42612 E194 G L A R T T S E T D F M T E Y
Maize Zea mays NP_001152745 397 44917 E219 G L A R T T S E T D F M T E Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39024 376 42833 D198 A R T K S E T D F M T E Y V V
Baker's Yeast Sacchar. cerevisiae Q00772 484 55617 R306 L A F D P Q K R I T V D E A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.6 97.6 86.7 N.A. 92 92.1 N.A. 30.3 N.A. 24.1 47.3 N.A. N.A. N.A. N.A. 32.7
Protein Similarity: 100 54.6 98 87.9 N.A. 93.2 93.3 N.A. 31 N.A. 32.8 59.1 N.A. N.A. N.A. N.A. 46.7
P-Site Identity: 100 6.6 86.6 0 N.A. 6.6 26.6 N.A. 0 N.A. 6.6 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 86.6 6.6 N.A. 13.3 40 N.A. 13.3 N.A. 6.6 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 26.2 26.1 N.A. 25.7 28.8 N.A.
Protein Similarity: 35 35 N.A. 34.6 40.5 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: 20 20 N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 22 0 0 8 0 8 15 8 8 8 8 8 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 8 0 8 15 8 15 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 15 0 8 15 15 8 22 0 % E
% Phe: 0 8 8 0 0 0 0 0 8 0 22 0 0 0 0 % F
% Gly: 36 0 8 15 15 0 15 8 0 8 15 0 8 8 0 % G
% His: 0 0 0 0 0 8 8 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 15 8 15 22 8 0 8 0 8 0 0 8 15 0 8 % K
% Leu: 15 15 0 0 0 8 0 0 0 8 15 15 8 8 8 % L
% Met: 0 8 0 0 0 0 0 0 0 15 0 15 0 0 8 % M
% Asn: 0 8 0 0 8 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 22 8 22 15 15 8 0 0 8 15 8 22 0 22 8 % P
% Gln: 0 15 0 15 8 15 8 0 0 8 8 8 8 15 15 % Q
% Arg: 0 15 0 22 8 8 0 15 0 0 0 8 8 8 0 % R
% Ser: 0 0 8 8 15 15 22 22 0 15 0 0 0 0 8 % S
% Thr: 0 8 8 0 15 15 15 8 43 8 8 0 22 0 0 % T
% Val: 8 0 8 0 8 8 0 8 0 0 8 0 15 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 29 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _